Black Mold Takes Hold and Story Told

DICON and Duke University Hospital physician Dr. Becky Smith has been working with other Duke Infectious Diseases Division faculty and Division of Cardiovascular and Thoracic Surgery faculty on a case of an invasive Curvularia infection in a patient who developed following bilateral orthotopic lung transplantation despite receiving post-transplant antifungal prophylaxis. This infection presented as mold colonies studding the interior surface of his chest tubes. Despite surgical washout of his bilateral pleural cavities and antifungal treatment with liposomal amphotericin B, micafungin, and isavuconazonium sulfate, the patient died.

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